SeqToKnow: NGS Workflows Platform
Scalable, reproducible and customizable NGS data analysis workflows on cloud for clinical diagnostics and translational research with automated report generation and interactive visualizations
Analysis Capabilities
Genomics
- Whole genome (WGS) and exome (WES/WXS) sequence analysis
- Germline and somatic variant calling
- Variant annotation and prioritization
Transcriptomics
- Bulk RNA-Seq data analysis
- Differential gene expression analysis
- Variant calling
- Biomarker discovery
Immunology
Single-cell sequencing data analysis
- B and T cell epitope predictions.
- Peptide-MHC class-I and -II binding predictions.
- Antibody (BCR) and T cell receptor (TCR) sequence analysis
- HLA-typing using sequencing data
Single-cell sequencing data analysis
Single-cell sequencing data analysis
Single-cell sequencing data analysis
- Gene expression
- Immune profiling
- Antibody (BCR) and T cell receptor (TCR) sequence analysis
- scATAC-Seq data analysis
BioIT
Single-cell sequencing data analysis
Metagenomics
- Cloud computing
- Database development and management
- Recommendations and management of IT infrastructure systems
Metagenomics
Single-cell sequencing data analysis
Metagenomics
- Functional metagenomics data analysis
- Taxonomic profiling
- Microbial transcriptomics
- Microbial genome assembly
Proteomics
Metabolomics
Metabolomics
- Analyze and assemble mass spectrometry data.
- Identification of MHC binding peptides using mass spectrometry
- Drug and drug target discovery and biomarker research
- Protein structure analysis
Metabolomics
Metabolomics
Metabolomics
- Biomarker discovery
- Drug safety screens
- Flux analysis
Epigenetics
Metabolomics
Epigenetics
- Whole Genome Bisulfite Sequencing
- Targeted Bisulfite Sequencing
- ATAC-Seq and ChIP-Seq data analysis